Studies on Heat Resistance

Studies on Resistance to Antibiotics

The discovery of gramicidin, penicillin, streptomycin, and the numerous other antibiotics known today has contributed materially to the list of therapeutic agents available against micro-organisms. However, the immediate enthusiasm which greeted their introduction has had to be checked by the realization that many of the important organisms affected readily develop resistance to the antibiotic ...

Comparative studies on micro heat exchanger optimisation

Although many methods for dealing with multi-objective optimisation (MOO) problems are available [Deb01] and successful applications have been reported [Coe01], the comparison between MOO methods applied to real-world problem was rarely carried out. This paper reports the comparison between MOO methods applied to a real-world problem, namely, the optimisation of a micro heat exchanger ( HEX). T...

Tumor Resistance Studies on In Vitro Studies on

Studies on microcirculation in insulin resistance

The overall aim of this thesis was to investigate the microcirculation in insulin resistance, with focus on the expression of endothelin-1, through a translational approach. Specific aims: 1) Investigate if circulating endothelin-1 levels predicts incident coronary heart disease events. 2) To assess if sex differences modify endothelin-1 as a predictor of type 2 diabetes. 3) To investigate if m...

Studies on Resistance against 5-Fluorouracil

Four different 5-fluorouracil (FU)-resistant tumor lines were developed by treating a drug-sensitive Ehrlich ascites tumor, ELD, with FU during 925—SO passages. Acetone powder extracts of the tumor lines were assayed for the following enzymes : uridine phosphorylase and kinase, deoxyuridine phosphorylase and kinase. In all four tumor lines significant decreases in uridine kinase activity occu...